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What is the Fosamprenavir calcium ?
Fosamprenavir calcium is white microcrystalline needles, while it's Molecular Formula is C25H34CaN3O9PS. HIV protease inhibitor; water soluble prodrug of amprenavir.
What is the CAS number for Fosamprenavir calcium ?
The CAS number of Fosamprenavir calcium is 226700-81-8.
More information of Fosamprenavir calcium 226700-81-8 are:
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Synonyms |
Carbamicacid,[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)-2-(phosphonooxy)propyl]-,C-[(3S)-tetrahydro-3-furanyl] ester, calcium salt (1:1) (9CI);Carbamic acid,N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)-2-(phosphonooxy)propyl]-,(3S)-tetrahydro-3-furanyl ester, calcium salt (1:1);Amprenavir phosphate calcium;(3S)-Tetrahydro-3-furyl ((alphaS)-alpha-((1R)-1-hydroxy-2-(N(sup 1)-isobutylsulfanilamido)ethyl)phenethyl)carbamate, calcium phosphate (ester) (1:1); |
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CAS?Number |
226700-81-8 |
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Molecular Formula |
C25H34CaN3O9PS |
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Molecular Weight |
623.67 |
|
Melting Point |
282-284 °C |
|
PSA |
201.57000 |
|
LogP |
5.44910 |
What is Fosamprenavir calcium (226700-81-8) used for?
Fosamprenavir (calcium salt) is an orally bioavailable prodrug of the HIV-1 protease inhibitor amprenavir . Fosamprenavir has improved solubility compared with amprenavir, and its pharmacokinetics, either during fasting or with a low- or high-fat meal, suggest that it could be effective using fewer tablets and a less complex dosing schedule than other HIV treatments. Formulations containing fosamprenavir are used for adult and pediatric patients with HIV infection, especially as an initial antiretroviral therapy.
InChI:InChI=1/C25H36N3O9PS.Ca/c1-18(2)15-28(39(33,34)22-10-8-20(26)9-11-22)16-24(37-38(30,31)32)23(14-19-6-4-3-5-7-19)27-25(29)36-21-12-13-35-17-21;/h3-11,18,21,23-24H,12-17,26H2,1-2H3,(H,27,29)(H2,30,31,32);/q;+2/t21-,23-,24+;/m0./s1
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